Stem Cells Restore Toddler's Congenital Hearing Loss

In a potentially revolutionary treatment, a two years old toddler born deaf has had her hearing restored after receiving stem cells from her banked umbilical cord blood. (Reported in ABC News)

Madeline Connor at age 1 year old was completely deaf in the right ear and had severe hearing loss on the left. Normally hearing aids or cochlear implant would have been the only options.

However, in January 2012 at the age of 2 years old, Madeline underwent a "simple" experiment whereby stem cells were infused into her damaged inner ear. The stem cells were derived from umbilical cord blood that was banked at the time of her delivery at the Memorial Hermann-Texas Medical Center.

Over the next 6 months, there has been dramatic improvement in her hearing. She is also now talking for the first time.

Madeline also is not the only child who has undergone this revolutionary stem cell treatment. Apparently, there are ten other children who are being followed after undergoing similar stem cell infusion derived from banked cord blood.

It must be stressed that though Madeline's progress is quite amazing, it is still too early to say if this is a "bona fide" treatment for congenital hearing loss.

• Will the improvement continue and more importantly, last over years to decades?
• Will it work for other children?
• What is the expected hearing improvement with stem cell infusion?
• Will it treat ALL forms of nerve-damaged hearing loss?
• Does it have to be stem cells derived from cord blood or are stem cells derived from other sources possible (i.e., skin)?
• Can adults with non-congential hearing loss also benefit?

I eagerly await the outcome of this FDA approved trial which hopefully will be published at some point in the near future.

I also eagerly await the protocol used to obtain and infuse the stem cells. I suspect the infusion of stem cells is similar to that done when steroids are infused into the ear for sudden hearing loss as shown in this video below. However, this is just a guess of mine.

Source:

Cord Blood Stem Cells Restore Toddler's Hearing. ABC News 7/11/12

Kissing the Ear Can Cause Permanent Hearing Loss

MSNBC reported 3/29/12 about a phenomenon called cochlear ear-kiss injury. This condition is when hearing loss occurs after a person kisses someone else over the ear, usually a mom over a baby's or child's ear.

Right after the kiss, a person can suffer from immediate and potentially permanent hearing loss along with other symptoms including ringing, sensitivity to sound, sound distortion, and aural fullness.

How or why does this occur?

With a kiss, a strong suction is created within the ear canal that pulls on the eardrum which tugs on the middle ear bones that can lead to turbulence within the inner ear.

Infants are particularly susceptible to this condition given their ear canals are SO small and the suction created by an adult kiss over the ear can be so strong.

There are other variations of this type of ear/hearing injury.

Barotrauma of the ear can lead to similar type issues due to sudden pressure changes from flying, parachute jumping, diving into water, SCUBA, snorkeling, etc.

Getting slapped over the ear can do the same thing as cochlear ear-kiss injury, but in reverse. Rather than suction from a kiss creating strong negative pressure within the ear canal, a slap over the ear creates sudden strong positive pressure.

At times, such pressure changes can get so severe that the eardrum can rupture.

Source:
Innocent 'kiss of deaf' can cause permanent hearing loss. MSNBC 3/29/12

The kiss of deaf: Four-year-old's big smooch left her mom with partial hearing loss. Newsday. June 7, 2008

New Video on Newborn Hearing Testing

Given how often we see newborns in need of hearing testing, we have produced a video showing how the two main types of non-verbal hearing tests are performed today: Auditory Brainstem Response (ABR) and Otoacoustic Emission (OAE).

Given newborns can not communicate whether they can hear or not, such hearing tests depend on the ability to detect nerve signals transmitting sound information from the ear all the way to the brain. This type of test is much like an EKG which can detect the electrical activity of the heart.

Watch the video to see how ABR and OAE hearing testing works in infants (as well as adults)!