Can Eye Drop Medications be Used in the Ear?

Can EYE drop medications be used in the EAR for ear problems like ear infections?

For the most part, absolutely.

For pretty much any EAR drop preparation, there is an equivalent EYE drop preparation which can be used safely in the ear.

Why does this matter?

It's because it may be cheaper for the patient if the EYE drop medication is prescribed rather than the EAR drop medication. Often, it is not unusual for a brand name ear drop medication to be available in generic eye drop form.

NOW... EAR drop medications should NOT be used in the EYE because preservatives used in eye drop preparations are much gentler than those used in ear drops due to the eyeball being much more sensitive compared to the ear. As such, it may burn if ear drops are used in the eye... but not vice-versa.

• Floxin (Ear) equivalent to Ocuflox (Eye)
• Ciprodex (Ear) equivalent to Ciloxan (Eye) without the steroid dexamethasone
• Cipro HC (Ear) equivalent to Ciloxan (Eye) without the steroid hydrocortisone
• Cortisporin (neomycin-polymyxin-hydrocortisone) is available in both eye and ear preparations
• Tobradex (Eye) can be used in the ear and is imprecisely similar to Cortisporin (Eye/Ear).

Pill Rather than Allergy Shots for Ragweed

If all goes well, in 2013 there will be a pill a patient can take rather than allergy shots to tone down the immune response to not only grasses (Grazax), but also ragweed.

The active ingredient in this ragweed pill is Ambrosia artemisifolia, the chemical found within ragweed that causes allergy symptoms.

Phase III trials with this pill taken once/day for 52 weeks conducted by Merck show a significant improvement in allergy symptoms by nearly 25%. Use of allergy medications like anti-histamines and steroid nasal sprays decreased by about 40%.

Just as in allergy shots, it is felt that repeated exposure to the actual allergen will induce immune tolerance. As such, rather than treating the symptoms as with anti-histamines, this medication will theoretically prevent the allergy from appearing in the first place.

Of course, side effects were present and akin to allergies it is supposed to prevent.

There is no published data yet, but results were presented at the 2012 AAAAI meeting.

Source:
New allergy pill may tame ragweed symptoms. MSNBC 3/4/12

Xylitol Nasal Flushes Helps Prevent Chronic Sinusitis

Over the years, there has been much about how beneficial a safe food additive called xylitolis in preventing infections. This naturally-occurring plant-based sugar substitute apparently has all sorts of anti-bacterial as well as anti-fungal properties. Given these properties, daily xylitol gum chewingor xylitol nasal sprayuse has been shown to help prevent recurrent acute ear infections and sinus infections... safe for use even in infants.

How may this occur? Toronto researchers figured out that xylitol inhibits the adherence of germs (burkholderia in the study) to airway linings thereby helping to prevent recurrent infections.

Another beneficial practice found to be helpful in preventing sinus infections are saline flushes to the nose. For those who don't realize the difference, saline flushes are different from saline nasal sprays in the volume of irrigation performed (think garden hose versus squirt bottle). Nasopurenasal flushes is being shown in the picture above (there are many different stylesbut all basically do the same thing).

Now what if we combine saline flushes with xylitol for those who suffer from particularly difficult chronic sinus infections???

Stanford University researchers conducted a small study (20 subjects) to see whether xylitol flushes (rather than nasal spray) to nose works even better than plain saline flushes to the nose. In spite of its small size, it was a prospective, randomized, double-blinded, controlled crossover pilot study.

What they found, at least in the short term, is that xylitol nasal irrigations resulted in greater improvement of chronic rhinosinusitis symptoms as compared to saline irrigations.


Reference:
Xylitol nasal irrigation in the management of chronic rhinosinusitis: A pilot study. The Laryngoscope Volume 121, Issue 11, pages 2468–2472, November 2011

A novel model to study bacterial adherence to the transplanted airway: inhibition of Burkholderia cepacia adherence to human airway by dextran and xylitol. J Heart Lung Transplant. 2004 Dec;23(12):1382-91.

A Story About a Sugar: The X-Factor. Blog by Dr. Faust

Xylitol as a prophylaxis for acute otitis media: systematic review. Int J Audiol. 2010 Oct;49(10):754-61.

A novel use of xylitol sugar in preventing acute otitis media. Pediatrics. 1998 Oct;102(4 Pt 1):879-84.

Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial. BMJ. 1996 Nov 9;313(7066):1180-4.

Failure of xylitol given three times a day for preventing acute otitis media. Pediatr Infect Dis J. 2007 May;26(5):423-7.

Xylitol administered only during respiratory infections failed to prevent acute otitis media. Pediatrics. 2002 Feb;109(2):E19.