Pill Rather than Allergy Shots for Ragweed

If all goes well, in 2013 there will be a pill a patient can take rather than allergy shots to tone down the immune response to not only grasses (Grazax), but also ragweed.

The active ingredient in this ragweed pill is Ambrosia artemisifolia, the chemical found within ragweed that causes allergy symptoms.

Phase III trials with this pill taken once/day for 52 weeks conducted by Merck show a significant improvement in allergy symptoms by nearly 25%. Use of allergy medications like anti-histamines and steroid nasal sprays decreased by about 40%.

Just as in allergy shots, it is felt that repeated exposure to the actual allergen will induce immune tolerance. As such, rather than treating the symptoms as with anti-histamines, this medication will theoretically prevent the allergy from appearing in the first place.

Of course, side effects were present and akin to allergies it is supposed to prevent.

There is no published data yet, but results were presented at the 2012 AAAAI meeting.

Source:
New allergy pill may tame ragweed symptoms. MSNBC 3/4/12

Allergy CURE in a Pill???

Well... possibly just for grasses at this time and only in Europe. Grazax®, a grass-pollen allergen tablet, is now (in Europe) available for children and is made by Allergy Company ALK-Abelló. Grazax is the ONLY non-injection immunotherapy licensed to treat children suffering from severe hay fever caused by grass pollen allergy.

Grazax has been available for use in adults in Europe since January 2007. It's a once daily, fast-melting tablet which is placed under the tongue. Traditionally, immunotherapy has been given by injection but the tablet formulation is more convenient and easier to use. Sublingual allergy drops has been around for much longer and is already offered by some practices in the United States.

Grazax (as far as I know) is not available in the United States... yet...