Poor Quality Sleep Contributes to High Blood Pressure

Obstructive sleep apnea (OSA) is known to cause all sorts of health problems beyond sleepiness. Medical problems include increased risk of stroke, heart attack, peripheral vascular disease, high blood pressure, etc. However, what researchers have recently found is that even if you do not have obstructive sleep apnea, if a person does not have enough "deep sleep" per night resulting in poor quality sleep, that also can increase risk of hypertension.

Researchers collected data on 784 men over the age of 65 who didn't have high blood pressure initially and followed them over the next 3 years. At home sleep studies were obtained initially and at follow-up to look at their sleep patterns as well as their blood pressure.

What they found was that individuals with poor quality sleep, reflected by reduced slow wave sleep (deep sleep), puts individuals at significantly increased risk of developing high blood pressure, and that this effect appeared to be independent of obstructive sleep apnea.

Read a CNN report here.

Reference:
Decreased Slow Wave Sleep Increases Risk of Developing Hypertension in Elderly Men. HYPERTENSION AHA.111.174409. Published online before print August 29, 2011,

Nasonex Sinus Implant for Chronic Sinusitis

The FDA on August 15, 2011 approved of a novel dissolvable sinus implant that slowly releases mometasone furoate steroid (same active ingredient as Nasonex steroid nasal spray) directly onto the sinus mucosa.

The spring-like implant is placed at the time of sinus surgery and automatically expands and conforms to the sinus cavity regardless of size and shape.

The theory is that by continuously delivering a low dose steroid directly to the sinus cavity, sinus inflammation will decrease and risk of scarring will decrease resulting in an overall decrease in chronic sinusitis for the patient after sinus surgery.

This is a GREAT idea and studies have born out its effectiveness. Hopefully other drug-eluting dissolvable stents like this will be developed in the future!

Developed by Intersect ENT, the implant is called "Propel."

Read about the FDA approval here.

References:
Safety and efficacy of a novel bioabsorbable, steroid eluting sinus stent. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY. 2011;1(1):23-32.

Advances in the Surgical Management of Chronic Sinusitis and Nasal Polyps. CURRENT ALLERGY AND ASTHMA REPORTS. Published online 08 February 2011

Controlled steroid delivery via bioabsorbable stent: Safety and performance in a rabbit model. AMERICAL JOURNAL OF RHINOLOGY & ALLERGY. November–December 2009, Vol. 23, No. 6.

Gluing Cut Blood Vessels Together

Gluing blood vessels together, just like gluing a cut garden hose together, does not seem like a great idea at first, but Stanford researchers just might have figured out how to do this safely and effectively.

Over the past century and still currently used today is to hand-sew the cut ends of the blood vessel together using stitches. This method of reattaching blood vessels is time-consuming and tedious, especially when the blood vessels are tiny.

In this new glue method which is FIVE times faster, a special substance is injected into the cut blood vessel on both ends called a poloxamer. This substance has the unique property of becoming an elastic solid when heated above body temperature which than turns into a biodegradable liquid that dissolves away when cooled.

In a nutshell, the steps are as follows:

1. The poloxamer is inserted into the blood vessel where is solidifies using a halogen lamp thereby keeping the lumen open.


2. The cut edges of the blood vessel are precisely reapproximated and "glued" together using dermabond, a substance currently used to "glue" together cut skin.


3. The blood vessel is allowed to cool down by taking away the halogen lamp and the poloxamer contained within the blood vessel melts and dissolves away.

So far, this procedure has only been done in animals, but since all of the components of this technique has already been FDA-approved for human use for other purposes, if proven to work, can rapidly be adopted for microvascular surgery in humans.

Reference:
Vascular anastomosis using controlled phase transitions in poloxamer gels. Nature Medicine (2011) doi:10.1038/nm.2424

Actress Maggie Q Suffers From Hearing Loss

American actress Maggie Q of Mission: Impossible III and TV show Nikita fame suffers from significant hearing loss due to a loud noise exposure from a movie set explosion.

Apparently, during shooting of an explosive stunt, her left eardrum was blown out while her right ear suffered mild hearing loss.

Such an injury could have been prevented with hearing protection.

Jay Leno Has a Degree in Speech Therapy

Yes... It is true!!!

Jay Leno admired by many for his comic personality had his beginnings as a speech therapist. He graduated in 1973 from Emerson College with a bachelor's degree in speech therapy. In order to help pay for his education, he worked in comedy clubs as well as an emcee in talent shows.

Who knew?

Reference:
Wikipedia